研究者情報 | 神奈川大学

キハラ　ノブヒロ Kihara Nobuhiro 木原　伸浩所属神奈川大学理学部理学科神奈川大学大学院理学研究科理学専攻（化学領域）職種教授
言語種別	英語
発行・発表の年月	2015/01
形態種別	学術雑誌
査読	査読あり
標題	The Cyclopentyl Group, As a Small but Bulky Terminal Group, Allows Rapid and Efficient Active Transport
執筆形態	共著
掲載誌名	Org. Lett.
巻・号・頁	17(1),pp.138-141
著者・共著者	Junya Nishiyama, Yoshimasa Makita, Nobuhiro Kihara
概要	Secondary ammonium salts bearing a cyclopentyl terminal group rapidly formed pseudorotaxane with 1.5 equiv of DB24C8. Acylation of the pseudorotaxane with 50 equiv of benzoyl chloride in the presence of 50 equiv of triethylamine in toluene afforded rotaxane, the product of active transport, in 95% yield. The cyclopentyl group is small enough to allow rapid formation of pseudorotaxane, and bulky enough to facilitate the quant. active transport by steric repulsion.
DOI	10.1021/ol5031469
ISSN	1523-7052