キハラ ノブヒロ   Kihara Nobuhiro
  木原 伸浩
   所属   神奈川大学  理学部 化学科
   職種   教授
言語種別 英語
発行・発表の年月 2015/01
形態種別 学術雑誌
査読 査読あり
標題 The Cyclopentyl Group, As a Small but Bulky Terminal Group, Allows Rapid and Efficient Active Transport
執筆形態 共著
掲載誌名 Org. Lett.
巻・号・頁 17(1),pp.138-141
著者・共著者 Junya Nishiyama, Yoshimasa Makita, Nobuhiro Kihara
概要 Secondary ammonium salts bearing a cyclopentyl terminal group rapidly formed pseudorotaxane with 1.5 equiv of DB24C8. Acylation of the pseudorotaxane with 50 equiv of benzoyl chloride in the presence of 50 equiv of triethylamine in toluene afforded rotaxane, the product of active transport, in 95% yield. The cyclopentyl group is small enough to allow rapid formation of pseudorotaxane, and bulky enough to facilitate the quant. active transport by steric repulsion.
DOI 10.1021/ol5031469
ISSN 1523-7052