キハラ ノブヒロ   Kihara Nobuhiro
  木原 伸浩
   所属   神奈川大学  理学部 化学科
   職種   教授
言語種別 英語
発行・発表の年月 1990/01
形態種別 学術雑誌
査読 査読あり
標題 Synthesis and Selective Molecular Recognition of a Macrotricyclic Receptor Having Crown Ether and Cyclophane Subunits as Binding Sites
執筆形態 共著
掲載誌名 J. Am. Chem. Soc.
巻・号・頁 112(3),pp.1144-1150
著者・共著者 Kazuhiko Saigo, Nobuhiro Kihara, Yukihiko Hashimoto, Ru-Jang Lin, Hiroshi Fujimura, Yoshihiro Suzuki, and Masaki Hasegawa
概要 The synthesis and selective mol. recognition of a new type of cylindrical, macrotricyclic receptor (I) having crown ether and cyclophane subunits as binding sites and a large hydrophobic cavity are described. Receptor I was synthesized by the stepwise construction of three individually prepd. subunits: bis(p-toluylsulfonamido)dibenzo-18-crown-6, a diaminocyclophane, and Et 4'-(bromomethyl)biphenyl-4-carboxylate. The interaction of I and various (ω-phenylalkyl)ammonium picrates, for which the no. of methylene units varies from 3 to 9, was examd., and they were found to form 1:1 complexes. The selectivity of I for the picrates was evaluated by comparing the stability consts. (Ks') of these complexes. The Ks' values of the complexes with (5-phenylpentyl)ammonium and (6-phenylhexyl)ammonium picrates were more than 3 times as large as those of the other complexes; i.e., I showed selective mol. recognition.
DOI 10.1021/ja00159a039
ISSN 0002-7863