キハラ ノブヒロ   Kihara Nobuhiro
  木原 伸浩
   所属   神奈川大学  理学部 化学科
   職種   教授
言語種別 英語
発行・発表の年月 1993/07
形態種別 学術雑誌
査読 査読あり
標題 Gallium Dichloride-Mediated Reductive Friedel-Crafts Reaction
執筆形態 共著
掲載誌名 Tetrahedron
巻・号・頁 49(27),pp.5969-5978
著者・共著者 Yukihiko Hashimoto, Kazuyuki Hirata, Hirotaka Kagoshima, Nobuhiro Kihara, Masaki Hasegawa, and Kazuhiko Saigo
概要 Treating carbonyl compds. or their di-Me acetals with arom. compds. in the presence of GaCl2 gave Friedel-Crafts alkylated adducts in good yields. Adducts are likely obtained by redn. of the carbonyl compds. or their di-Me acetals, followed by the Friedel-Crafts reaction in one-pot. This is the first org. synthetic method with GaCl2, low valent gallium. Thus, PhCHO reacted with PhOMe in CS2 in the presence of Ga2Cl4 at 0° to give 77% a mixt. of p- and o-MeOC6H4CH2Ph in the ratio of 44:56 resp.
DOI 10.1016/S0040-4020(01)87183-0
ISSN 0040-4020