キハラ ノブヒロ   Kihara Nobuhiro
  木原 伸浩
   所属   神奈川大学  理学部 化学科
   職種   教授
言語種別 英語
発行・発表の年月 1993/11
形態種別 学術雑誌
査読 査読あり
標題 A Novel Michael Reaction of Silyl Enol Ethers via Hetero Diels-Alder Reaction with Alkylidene-Meldrum's Acid
執筆形態 共著
掲載誌名 Tetrahedron Lett.
巻・号・頁 34(46),pp.7437-7440
著者・共著者 Shigeo Mizukami, Nobuhiro Kihara, and Takeshi Endo
概要 Alkylidene Meldrum's acid I (R = Me, Et, Ph) easily reacted with silyl enol ethers, R1CH:CR2OSiMe3 (e.g., R1 = H, R2 = Ph) without any catalyst to afford hetero Diels-Alder adducts which could be quant. hydrolyzed to obtain Michael adducts II in good yields. The Michael adducts II could be obtained diastereoselectively and could be converted to corresponding δ-ketoesters quant.
DOI 10.1016/S0040-4039(00)60146-6
ISSN 0040-4039