キハラ ノブヒロ   Kihara Nobuhiro
  木原 伸浩
   所属   神奈川大学  理学部 化学科
   職種   教授
言語種別 日本語
発行・発表の年月 1997/05
形態種別 著書
招待 招待あり
標題 異種ホストの協同効果
執筆形態 共著
掲載誌名 超分子を目指す化学(季刊化学総説)
出版社・発行元 学会出版センター
巻・号・頁 133-143頁
著者・共著者 木原 伸浩、西郷 和彦
概要 A review with 25 refs. Highly selective mol. recognition can be realized by cumulation and organization of various types of recognition sites in a host mol. A cylindrical macrotricyclic receptor I having a crown ether unit as an electrostatic interaction site and a cyclophane unit as a hydrophobic interaction site facing each other at a const. distance by 2 rigid bridges was designed. Receptor I formed 1:1 complexes with ω-phenylalkylammonium picrates II, and the complexes having a 5-6 methylene chain were 3-4 times more stable than the others. From NMR analyses, cooperative phenomenon of electrostatic and hydrophobic interactions was demonstrated. In general, the increase of the hydrophobic interaction between the cyclophane unit in I and the benzene ring in II, which caused the decrease of ΔH, restricted the mobility of benzene ring, resulting in the decrease of ΔS. The selectivity in the complexation of I with II decreased at a higher temp.