研究者情報 | 神奈川大学

キハラ　ノブヒロ Kihara Nobuhiro 木原　伸浩所属神奈川大学理学部理学科神奈川大学大学院理学研究科理学専攻（化学領域）職種教授
言語種別	英語
発行・発表の年月	1999/11
形態種別	学術雑誌
査読	査読あり
標題	Efficient Radical Oxygenation of alpha-Iodocarboxylic Acid Derivatives,
執筆形態	共著
掲載誌名	Org. Lett.
巻・号・頁	1(9),pp.1419-1422
著者・共著者	Nobuhiro Kihara, Cyril Ollivier, and Philippe Renaud
概要	Treatment of α-iodocarboxylic acid derivs. with 2 equiv of triethylborane under an oxygen atm. gives the corresponding α-hydroxy acid derivs. This method is based on an iodine atom transfer from the Et radical, generated by the reaction of triethylborane and oxygen, with the α-iodocarbonyl compd. It offers several advantages over classical ionic substitution reactions: no elimination product is obsd., tertiary iodides are efficiently converted to alcs., and finally, this one-step procedure works with substrates sensitive to nucleophiles.
DOI	10.1021/ol990971n
ISSN	1523-7060