研究者情報 | 神奈川大学

イワクラ　イズミ Iwakura Izumi 岩倉　いずみ所属神奈川大学化学生命学部応用化学科神奈川大学大学院工学研究科工学専攻（応用化学領域）職種教授
言語種別	英語
発行・発表の年月	2003/10
形態種別	学術雑誌
査読	査読あり
標題	Enantioselective Borodeuteride Reduction of Aldimines Catalyzed by Cobalt Complexes: Preparation of Optically Active Deuterated Primary Amines.
執筆形態	共著
掲載誌名	Organic Letters
掲載区分	国外
巻・号・頁	5(20),pp.3555-3558
著者・共著者	Daichi Miyazaki, Kohei Nomura, Tatsuya Yamashita, Izumi Iwakura, Taketo Ikeno, Tohru Yamada
概要	The enantioselective borodeuteride reduction catalyzed by optically active β-ketoiminato cobalt complexes was applied to N-(di(o-tolyl)phosphinyl)aldimines to afford the corresponding optically active deuterated primary amines in high yields with high enantiomeric excesses after simple deprotection. The present deuteride reduction of aldimines is in the opposite sense of the enantioselective for the previously reported borohydride reduction of ketones or diphenylphosphinyl aldimines. The stereochemical course in these enantioselective reductions is discussed. Hot Article
DOI	https://doi.org/10.1021/ol0349920
researchmap用URL	https://pubs.acs.org/doi/10.1021/ol0349920