研究者情報 | 神奈川大学

キハラ　ノブヒロ Kihara Nobuhiro 木原　伸浩所属神奈川大学理学部理学科神奈川大学大学院理学研究科理学専攻（化学領域）職種教授
言語種別	英語
発行・発表の年月	1990/01
形態種別	学術雑誌
査読	査読あり
標題	Synthesis and Selective Molecular Recognition of a Macrotricyclic Receptor Having Crown Ether and Cyclophane Subunits as Binding Sites
執筆形態	共著
掲載誌名	J. Am. Chem. Soc.
巻・号・頁	112(3),pp.1144-1150
著者・共著者	Kazuhiko Saigo, Nobuhiro Kihara, Yukihiko Hashimoto, Ru-Jang Lin, Hiroshi Fujimura, Yoshihiro Suzuki, and Masaki Hasegawa
概要	The synthesis and selective mol. recognition of a new type of cylindrical, macrotricyclic receptor (I) having crown ether and cyclophane subunits as binding sites and a large hydrophobic cavity are described. Receptor I was synthesized by the stepwise construction of three individually prepd. subunits: bis(p-toluylsulfonamido)dibenzo-18-crown-6, a diaminocyclophane, and Et 4'-(bromomethyl)biphenyl-4-carboxylate. The interaction of I and various (ω-phenylalkyl)ammonium picrates, for which the no. of methylene units varies from 3 to 9, was examd., and they were found to form 1:1 complexes. The selectivity of I for the picrates was evaluated by comparing the stability consts. (Ks') of these complexes. The Ks' values of the complexes with (5-phenylpentyl)ammonium and (6-phenylhexyl)ammonium picrates were more than 3 times as large as those of the other complexes; i.e., I showed selective mol. recognition.
DOI	10.1021/ja00159a039
ISSN	0002-7863