研究者情報 | 神奈川大学

イブカ　アキコ Ibuka Akiko 井深　章子所属神奈川大学化学生命学部生命機能学科神奈川大学大学院理学研究科理学専攻（生物科学領域）職種教授
言語種別	英語
発行・発表の年月	2015/09
形態種別	学術雑誌
査読	査読あり
標題	Long-Chain Fatty Acids Elicit a Bitterness-Masking Effect on Quinine and Other Nitrogenous Bitter Substances by Formation of Insoluble Binary Complexes
執筆形態	共著
掲載誌名	Journal of Agricultural and Food Chemistry
掲載区分	国外
出版社・発行元	American Chemical Society
巻・号・頁	63(38),pp.8493-8500
著者・共著者	Kayako Ogi, Haruyuki Yamashita, Tohru Terada, Ryousuke Homma, Akiko Shimizu-Ibuka, Etsuro Yoshimura, Yoshiro Ishimaru, Keiko Abe, Tomiko Asakura
概要	Using isothermal titration calorimetry and NMR, we revealed the complex formation between the fatty acids and bitter substances, and also the formation of hydrogen bonds between the nitrogen atoms of the bitter substances and the carboxyl groups of the fatty acids. When sodium laurate and the hydrochloride salt of quinine were mixed in water, an equimolar complex formed as insoluble heterogeneous needlelike crystals. These results suggested that fatty acids interact directly with bitter substances through hydrogen bonds and hydrophobic interactions to form insoluble binary complexes that mask bitterness.
DOI	10.1021/acs.jafc.5b03193
ISSN	15205118
PMID	26365517