研究者情報 | 神奈川大学

イワクラ　イズミ Iwakura Izumi 岩倉　いずみ所属神奈川大学化学生命学部応用化学科神奈川大学大学院工学研究科工学専攻（応用化学領域）職種教授
言語種別	英語
発行・発表の年月	2011/01
形態種別	学術雑誌
査読	査読あり
標題	"Click-made" biaryl-linker improving efficiency in protein labeling for the membrane target protein of a bioactive compound.
執筆形態	共著
掲載誌名	Organic & Biomolecular Chemistry,
掲載区分	国外
巻・号・頁	9(1),pp.83-85
著者・共著者	Yoko Nakamura, Sho Inomata, Makoto Ebine, Yoshiyuki Manabe, Izumi Iwakura, Minoru Ueda
概要	We report on the design, synthesis and assessment of a novel biaryl-linked (BArL) molecular probe for the exploration of low-abundant target proteins for bioactive compounds based on the activity based protein profiling (ABPP) approach. Surprisingly, the performance of the BArL probe was better than that of the stepwise tagging approach that is considered to be the most effective method used in ABPP study.
DOI	https://doi.org/10.1039/C0OB00843E
researchmap用URL	https://pubs.rsc.org/en/content/articlelanding/2011/OB/C0OB00843E#!divAbstract