フジタ ミサト   Fujita Misato
  藤田 深里
   所属   神奈川大学  理学部 生物科学科
   職種   助教
言語種別 日本語
発行・発表の年月 2018
形態種別 大学・研究所等紀要
標題 ゼブラフィッシュ血管内皮細胞の初期分化
執筆形態 共著
掲載誌名 Science Journal of Kanagawa University
掲載区分国内
出版社・発行元 神奈川大学 総合理学研究所
巻・号・頁 29,83-88頁
著者・共著者 藤田深里, 磯貝純夫
概要 Early differentiation of vascular endothelial cells is indispensable for the proper patterning and lumen formation of blood vessels. The vascular network forms in a reproducible and evolutionarily conserved manner, and their molecular mechanisms of formation have been markedly focused on. However, the differentiation process of vascular progenitors, angioblasts, remains unclear. Here, we report several tools to detect and analyze undifferentiated vascular endothelial cells in zebra sh embryos, including the vascular-speci c transgenic lines, inhibi- tor treatments, and 3D reconstruction technique of electron microscopic serial images.