イブカ アキコ   Ibuka Akiko
  井深 章子
   所属   神奈川大学  化学生命学部 生命機能学科
    神奈川大学大学院  理学研究科 理学専攻(生物科学領域)
   職種   教授
言語種別 英語
発行・発表の年月 2011/09
形態種別 学術雑誌
査読 査読あり
標題 Effects of Peanut-Skin Procyanidin A1 on Degranulation of RBL-2H3 Cells
執筆形態 共著
掲載誌名 BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
掲載区分国外
出版社・発行元 TAYLOR&FRANCIS LTD
巻・号・頁 75(9),pp.1644-1648
著者・共著者 Keisuke Tomochika,Akiko Shimizu-Ibuka,Tomoko Tamura,Kiyoshi Mura,Naoki Abe,Jun-ichi Onose,Soichi Arai
概要 Peanut skin contains large amounts of polyphenols having antiallergic effects. A low-molecular-weight fraction from peanut-skin extract (PSEL) also had inhibitory activity against allergic degranulation. A main polyphenol in PSEL was was identified as procyanidin A1. Our results indicate that peanut-skin procyanidin Al inhibits degranulation downstream of protein kinase C activation or Ca2+ influx from an internal store in RBL-2H3 cells.
DOI 10.1271/bbb.110085
ISSN 09168451