研究者情報 | 神奈川大学

キハラ　ノブヒロ Kihara Nobuhiro 木原　伸浩所属神奈川大学理学部理学科神奈川大学大学院理学研究科理学専攻（化学領域）職種教授
言語種別	英語
発行・発表の年月	2021/03
形態種別	学術雑誌
査読	査読あり
標題	Synthesis and kinetic resolution of directional isomers of [2]rotaxanes bearing a lariat crown ether wheel
執筆形態	共著
掲載誌名	Supramolecular Chemistry
掲載区分	国外
出版社・発行元	Taylor and Francis
巻・号・頁	33(1-2),pp.1-7
著者・共著者	Yoshimasa Makita, Nobuhiro Kihara, Toshikazu Takata
概要	Rotaxanes can have topological isomers because of their mechanically interlocked axle and wheel components. Directional isomers are formed when the rotaxanes are constructed using an asymmetric axle and a three-dimensional non-symmetrical wheel. In this work, directional isomers of [2]rotaxanes were synthesised using lariat dibenzo-24-crown-8 ether as a non-symmetrical wheel component and a sec-ammonium salt axle. Control over the directional isomer ratio of [2]rotaxanes was achieved, as demonstrated by kinetic resolution via N-acetylation of the [2]rotaxanes.