研究者情報 | 神奈川大学

キハラ　ノブヒロ Kihara Nobuhiro 木原　伸浩所属神奈川大学理学部理学科神奈川大学大学院理学研究科理学専攻（化学領域）職種教授
言語種別	英語
発行・発表の年月	1993/11
形態種別	学術雑誌
査読	査読あり
標題	A Novel Michael Reaction of Silyl Enol Ethers via Hetero Diels-Alder Reaction with Alkylidene-Meldrum's Acid
執筆形態	共著
掲載誌名	Tetrahedron Lett.
巻・号・頁	34(46),pp.7437-7440
著者・共著者	Shigeo Mizukami, Nobuhiro Kihara, and Takeshi Endo
概要	Alkylidene Meldrum's acid I (R = Me, Et, Ph) easily reacted with silyl enol ethers, R1CH:CR2OSiMe3 (e.g., R1 = H, R2 = Ph) without any catalyst to afford hetero Diels-Alder adducts which could be quant. hydrolyzed to obtain Michael adducts II in good yields. The Michael adducts II could be obtained diastereoselectively and could be converted to corresponding δ-ketoesters quant.
DOI	10.1016/S0040-4039(00)60146-6
ISSN	0040-4039