研究者情報 - 太田　安隆

（最終更新日：2024-04-01 10:34:41）

  オオタ　ヤスタカ   Ohta Yasutaka
  太田　安隆
   所属   神奈川大学理学部理学科

神奈川大学大学院理学研究科理学専攻（生物科学領域）

職種教授

■ 専門分野

細胞生物学

■ 学位等

理学博士

■ 著書・論文歴

1.	論文	FilGAP controls cell-extracellular matrix adhesion and process formation of kidney podocytes. FASEB J. 38(5) （共著） 2024/05
2.	論文	RSK/GSK3 mediated phosphorylation of FilGAP regulates chemotactic cancer cell invasion. PNAS Nexus （共著） 2024/02
3.	論文	FilGAP regulates tumor growth in Glioma through the regulation of mTORC1 and mTORC2. Sci Rep. （共著） 2023/12
4.	論文	FilGAP, a GAP for Rac1, down-regulates invadopodia formation in breast cancer cells. Cell Struct. Funct. 48(2),pp.161-174 （共著） 2023/09
5.	論文	Endosomal Localization of RacGAP Protein ARHGAP22 Regulates its GAP Activity in Human Melanoma Cells. 42(12),pp.5763-5771 （共著） 2022/12
6.	論文	FilGAP, a Rho/Rho-associated protein kinase-regulated GTPase-activating protein for Rac, controls tumor cell migration. Mol. Biol. Cell 23,pp.4739-4750 （共著） 2021/12
7.	論文	FilGAP, a GAP protein for Rac, regulates front-rear polarity and tumor cell migration through the ECM. FASEB journal 35(4) （共著） 2021/04
8.	論文	Involvement of Nlrp9a/b/c in mouse preimplantation development. Reproduction 160(2),pp.181-191 （共著） 2020/08
9.	論文	AGAP1 regulates subcellular localization of FilGAP and control cancer cell invasion. Biochem Biophys Res Commun. 522,pp.676-683 （共著） 2020/02
10.	論文	FilGAP regulates distinct stages of epithelial tubulogenesis. Biochem Biophys Res Commun. 514(3),pp.742-749 （共著） 2019/06
11.	論文	Role of ARHGAP24 in ADP ribosylation factor 6 (ARF6)-dependent pseudopod formation in human breast carcinoma cells. Anticancer Res. 37(9),pp.4837-4844 （共著） 2017/09
12.	論文	The role of FilGAP, a Rac-specific Rho GTPase-activating protein, in tumor progression and behavior of astrocytomas. Cancer Med. 5,pp.3412-3425 （共著） 2016/12
13.	論文	The RacGAP protein FilGAP is a negative regulator of chemokine-promoted lymphocyte migration. FEBS Lett. 590(10),pp.1395-1408 （共著） 2016/04
14.	論文	Src Family Tyrosine Kinase Signaling Regulates FilGAP through Association with RBM10. PLOS ONE （共著） 2016/01
15.	論文	Afadin is localized at cell-cell contact sites in mesangial cells and regulates migratory polarity. Lab Invest. 96(1),pp.49-59 （共著） 2016/01
16.	論文	Phosphorylation of Serine 402 Regulates RacGAP Activity of FilGAP. J. Biol. Chem. 290(43),pp.26328-26338 （共著） 2015/10
17.	論文	FilGAP, a Rho/ROCK-regulated GAP for Rac controls adherens junctions in MDCK cells. J. Cell Sci. 128,pp.2047-2056 （共著） 2015/06
18.	論文	FilGAP, a Rac-specific Rho GTPase-activating protein, is a novel prognostic factor for follicular lymphoma. Cancer Med. 4,pp.808-818 （共著） 2015/06
19.	論文	Afadin regulates RhoA/Rho-associated protein kinase signaling to control formation of actin stress fibers in kidney podocytes. Cytoskeleton (Hoboken) 72,pp.146-156 （共著） 2015/03
20.	論文	Preferential targeting of p39-activated Cdk5 to Rac1-induced lamellipodia. Mol. Cell. Neurosci. 61,pp.34-45 （共著） 2014/07
21.	論文	ARHGAP22 localizes at endosomes and regulates actin cytoskeleton. PLoS ONE （共著） 2014/06
22.	論文	Arf6 acts through FilGAP to down-regulate Rac and regulates plasma membrane blebbing. J. Biol. Chem. 289,pp.9675-9682 （共著） 2014/04
23.	論文	Filamin associates with stress signaling kinases MKK7 and MKK4 and regulates JNK activation. Biochem. J. 427,pp.237-245 （共著） 2010/03
24.	論文	The NPIY motif in the integrin b1 tail dictates the requirement for talin-1 outside-in signaling J. Cell Sci. 123,pp.1216-1226 （共著） 2010
25.	論文	The role of FilGAP-filamin A interactions in mechanoprotection. Mol. Biol. Cell 20,pp.1269-1279 （共著） 2009/03
26.	論文	Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration. J. Cell Biol. 175,pp.555-562 （共著） 2006/11
27.	論文	FilGAP, a GTPase Activating Protein for Rac Binds Filamin A to Control Actin Remodeling. Nature Cell Biol. 8,pp.803-814 （共著） 2006/08
28.	論文	Rac1 null mouse embryonic fibroblasts are motile and respond to PDGF. Mol. Biol. Cell 17,pp.2377-2390 （共著） 2006/05
29.	論文	Filamin A-bound REBP2bCBFb is retained in the cytoplasm and prevented from functionaing as a partners of the Runx1 transcription factor. Mol. Cell. Biol 25,pp.1003-1012 （共著） 2005/02
30.	論文	Ribosomal S6 kinase (RSK) regulates phosphorylation of filamin A on an important regulatory site. Mol. Cell. Biol. 24,pp.3025-3035 （共著） 2004/04
31.	論文	The carboxy-terminal plecstrin homology domain of ROCK interacts with filamin-A. Biochem. Biophys. Res. Commun. 301,pp.886-890 （共著） 2003/02
32.	論文	Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adaptor molecules. Mol. Cell. Biol. 22,pp.8721-8734 （共著） 2002/12
33.	論文	Filamin is essential in actin cytoskeleyal assembly mediated by p21-activated kinase 1. Nature Cell Biol. 4,pp.681-690 （共著） 2002/09
34.	論文	The exocyst complex binds the small GTPase RalA to mediate filopodia formation. Nature Cell Biol. 4,pp.73-78 （共著） 2002/01
35.	論文	Filamin associates with Smads and regulates TGF-b signaling. J. Biol. Chem. 276,pp.17871-17877 （共著） 2001/05
36.	論文	The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin. Nature Cell Biol. 2,pp.888-892 （共著） 2000/12
37.	論文	The small GTPase Ra1A targets filamin to induce filopodia. Proc Nat Acad Sci USA 96,pp.2122-2128 （共著） 1999/03
38.	論文	Actin-binding protein 280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor- activation of SAPK in melanoma cells. J Biol Chem. 272,pp.2620-2628 （共著） 1997/01
39.	論文	Phosphorylation of actin-binding protein 280 growth factors is mediated by p90 ribosomal protein S6 kinase. 271,pp.11858-11864 （共著） 1996/05
40.	論文	Actin filament cross-linking by chicken gizzard filamin is regulated by phosphorylation in vitro. 34,pp.6745-6754 （共著） 1995/05
41.	論文	Ligand-sensitive binding of the high-affinity IgG receptor (FcgR1) to actin-binding protein. Cell 67,pp.275-282 （共著） 1991/10
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